All trial participants will fill-out Quality of Life (QoL) questionnaires (SF-36 and EQ-5D) at time of inclusion and at each follow-up. We are interested in determining the effect of Aspirin 160 mg on Health-related Quality of Life outcome measures. The participants can fill out the QoL questionnaires either on-line by logging into ViewdocMe, written, or by-proxy by contacting an ASAC study nurse. The QoL forms take approximately 10 minutes to fill out.